Friday, July 19, 2013

Is There a Cure for Membranous Glomerulonephritis

Glomerulonephritis, also known as glomerular nephritis. It is featured with inflammation of glomeruli or small blood vessels in the kidneys. Membranous glomerulonephritis is one of types of glomerulonephritis. Is there a cure for membranous glomerulonephritis?

Membranous glomerulonephritis (MGN), a relatively common type of glomerulonephritis in adults.Prognosis follows the rule of thirds: one-third remain with MGN indefinitely, one-third remit, and one-third progress to end-stage renal failure. As the glomerulonephritis progresses, the tubules of the kidney become infected, leading to atrophy and hyalinisation. The kidney appears to shrink. Treatment with corticosteroids is attempted if the disease progresses.However, corticosteroids alone are not enough to cure membranous glomerulonephritis at all.

Membranous glomerulonephritis is an immune-mediated disorder with immune complexes in kidneys. The immune complexes can cause inflammation in kidneys, thus resulting in progressive inflammation in kidneys. While there is no a cure for membranous glomerulonephritis, certain treatments can stop its progression and even reverse kidney damage.

Immunotherapy is a recommended treatment for membranous glomerulonephritis. Immunotherapy is a medical term defined as the "treatment of disease by inducing, enhancing, or suppressing an immune response". In treating glomerulonephritis, immunotherapy can suppress the inflammatory response and build normal immune system. Additionally, it can stimulate the self-regeneration of kidney tissues to enhance renal function. In this way, the patients will be able to stop disease progression and developing kidney failure completely.

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